β-tubulin Antibody – 166Er

Catalog: 716601                                           Clone: D3U1W                                            Isotype: Mouse IgG2b
Reactivity: Human*, Mouse, Rat, Hamster, Monkey
Storage: β-tubulin antibody is supplied in antibody stabilizer with 0.05% sodium azide. Store a 4°C

IHC: β-tubulin antibody staining of  FFPE human tonsil

MIBI: β-tubulin antibody staining (cyan) of FFPE human tonsil, counterstained with dsDNA (magenta)

IHC: β-tubulin antibody staining of  FFPE human lung

MIBI: β-tubulin antibody staining
(cyan) of FFPE human lung,  counterstained with dsDNA  (magenta)

Background: The cytoskeleton is composed of microfilaments, intermediate filaments, and microtubules.  β-tubulin, together with α-tubulin, forms heterodimers that serve as the building blocks for microtubules.  The structure of microtubules is dynamically regulated in processes related to cell movement, cytoplasmic transport, and chromosome alignment during meiosis/mitosis. β-tubulin is broadly expressed in eukaryotic cells. β-tubulin is the target of several anti-tubulin agents used in the treatment of cancer.

Validation: Each lot of conjugated β-tubulin antibody is quality control tested by MIBIscope™ analysis of stained tissue microarray using the appropriate positive and negative tissue field of views and are pathologist verified.

Recommended Usage: 1 uL of β-tubulin antibody per 100 uL staining volume using the MIBI™ Staining Protocol.
For optimal results, antibody should be titrated for each desired application.  Suggested starting range is 1:100.

MIBI technology: Learn more about MIBI Technology, a multiplex IHC technology with unmatched sensitivity and true subcellular resolution.

References

  • Janke, C. The tubulin code: Molecular components, readout mechanisms, and functions. J Cell Biol. 2014; 206 (4)  461-472.

* Conjugate tested on human tissue.

Contact Us

We are glad that you prefer to contact us. Please fill our short form and one of our friendly team members will contact you back.


Immuno-oncology/CancerNeuroscienceInfectious DiseaseImmunologyStem CellOther


255

X
Contact Us

We are using cookies on our website

Please confirm, if you accept our tracking cookies. You can also decline the tracking and continue to visit our website without any data sent to third-party services.