CD3 Antibody – 159Tb

Catalog: 715901                                            Clone: D7A6E                                          Reactivity: Human*
Storage: CD3ɛ antibody is supplied in protein-based stabilizer with 0.05% sodium azide. Store at 4°C
IHC: CD3ɛ antibody staining of FFPE
human tonsil
MIBI: CD3ɛ antibody staining (cyan) of FFPE human tonsil, counterstained with dsDNA (magenta)
IHC: CD3ɛ antibody staining of FFPE
human thymus
MIBI: CD3ɛ antibody staining (cyan) of FFPE human thymus; for clarity dsDNA is not  shown
Background: CD3 is found on all mature T cells, serving important roles for T cell development. CD3 is part of the T cell receptor that recognizes antigen, resulting in the activation of signaling pathways. During T cell development the intensity of the response to antigen is tightly controlled to select for responsive T cells that are not autoreactive. In disease, the lack of CD3 expression is associated with a severe combined immunodeficiency (SCID) characterized by impairment of both humoral and cell-mediated immunity.

Validation: Each lot of conjugated CD3 antibody is quality control tested by MIBIscope™ analysis of stained tissue microarray using the appropriate positive and negative tissue field of views and are pathologist verified.

Recommended Usage: 1 uL of CD3 antibody per 100 uL staining volume using the MIBI™ Staining Protocol.
For optimal results, antibody should be titrated for each desired application.  Suggested starting range is 1:100.

MIBI technology: Learn more about MIBI Technology, a multiplex IHC technology with unmatched sensitivity and true subcellular resolution.


  • Guy, C. S. and Vignali, D. A. Organization of proximal signal initiation at the TCR: CD3 complex. Immunological
    Reviews. 2009; 232: 7-21.

* Conjugate tested on human tissue.

Contact Us

Let us know how we can help you.

    Immuno-oncology/CancerNeuroscienceInfectious DiseaseImmunologyStem CellOther


    Contact Us

    We are using cookies on our website

    Please confirm, if you accept our tracking cookies. You can also decline the tracking and continue to visit our website without any data sent to third-party services.