CD38 Antibody – 174Yb

Catalog: 717403 
Clone: E7Z8C
Isotype: Rabbit IgG
Reactivity: Human*
Application: MIBI-FFPE
Storage: Supplied in antibody stabilizer with 0.05% sodium azide. Store at 4°C

IHC: CD38 staining of FFPE human colon
MIBI: CD38 staining (cyan) of FFPE human colon, counterstained with dsDNA (magenta)
IHC: CD38 staining of FFPE human appendix
MIBI: CD38 staining (cyan) of FFPE human appendix, counterstained with dsDNA (magenta)
Background: CD38 is a glycoprotein found on the surface of many white blood cells, including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 expression is useful in identifying plasma cells and myelomas, and as a marker for activated B and T cells. CD38 expression also has prognostic implication in chronic lymphocytic leukemia.

Validation: Each lot of conjugated antibody is quality control tested by staining tissue following the MIBI Staining Protocol optimized for the applicable tissue format with subsequent MIBIscope analysis using the appropriate positive and negative tissue field of views. These results are pathologist verified.

Recommended Usage: Human FFPE: 1:100 dilution.
For optimal results, the antibody should be titrated for each desired application.

MIBI technology: Learn more about MIBI Technology, a multiplex IHC technology with unmatched sensitivity and true subcellular resolution.

Shaji Kumar et al. Immunophenotyping in multiple myeloma and related plasma cell disorders. Best Pract Res Clin Haematol. 2010 Sep; 23(3): 433-451.

Chuan He et al. Prognostic significance of CD38 for chronic lymphocytic leukemia: a meta-analysis. Int J Clin Exp Med 2017; 10(3): 4305-4312.

* Conjugate tested on human tissue.

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