Helios Antibody – 160Gd
Validation: Each lot of conjugated antibody is quality control tested by staining tissue following the MIBI Staining Protocol optimized for the applicable tissue format with subsequent MIBIscope analysis using the appropriate positive and negative tissue field of views. These results are pathologist verified.
Recommended Usage: Human FFPE: 1:100 dilution.
For optimal results, the antibody should be titrated for each desired application.
MIBI technology: Learn more about MIBI™ Technology, a multiplex IHC technology with unmatched sensitivity and true subcellular resolution.
Ian Baine et al. Helios induces epigenetic silencing of IL2 gene expression in regulatory T cells. J of Immunology. 2013 Feb 1;190(3):1008-16.
K Hahm et al. Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin. Genes Dev. 1998 Mar 15;12(6):782-96.
* Conjugate tested on human tissue.