Keratin Antibody – 165Ho

Catalog: 716501                                        Clone: AE1/AE3                                         Isotype: Mouse IgG1
Reactivity: Human*
Storage: Keratin antibody is supplied in antibody stabilizer with 0.05% sodium azide. Store a 4°C

IHC: Keratin staining of FFPE human placenta

MIBI: Keratin staining (cyan) of FFPE human placenta, costained with dsDNA (magenta)

IHC: Keratin staining of FFPE human thymus

MIBI: Keratin staining (cyan) of FFPE human thymus, costained with dsDNA (magenta)

Background: Keratin is a fibrous structural protein that assembles into bundles to form intermediate filaments of the cytoskeleton within epithelial cells. The present antibody is a mix of clones AE1 and AE3 that recognize most acidic and basic cytokeratin family members (CK1, 2, 3, 4, 5, 6, 7, 8, 10, 14, 15, 16 and 19). Specific tumor types express these keratins making this a useful marker in the identification of tumor cells and of the origin of a neoplasm.

Validation: Each lot of conjugated keratin antibody is quality control tested by MIBIscope™ analysis of stained tissue microarrays using the appropriate positive and negative tissue field of views and are pathologist verified.

Recommended Usage: 1 uL of keratin antibody per 100 uL staining volume using the MIBI™ Staining Protocol.
For optimal results, antibody should be titrated for each desired application.  Suggested starting range is 1:100.

MIBI technology: Learn more about MIBI Technology, a multiplex IHC technology with unmatched sensitivity and true subcellular resolution.

References

  • Jacob, J.T., Coulombe, P.A., Kwan, R., Omary, M.B. Types I and II Keratin Intermediate Filaments. Cold Spring Harbor Perspect Biol. 2018;10(4).

* Conjugate tested on human tissue.

Contact Us

We are glad that you prefer to contact us. Please fill our short form and one of our friendly team members will contact you back.


Immuno-oncology/CancerNeuroscienceInfectious DiseaseImmunologyStem CellOther


255

X
Contact Us

We are using cookies on our website

Please confirm, if you accept our tracking cookies. You can also decline the tracking and continue to visit our website without any data sent to third-party services.