PD-L1 Antibody – 149Sm
Catalog: 714901 Clone: E1L3N Isotype: Rabbit IgG
Storage: PD-L1 antibody is supplied in antibody stabilizer with 0.05% sodium azide. Store at 4°C
IHC: PD-L1 antibody staining of FFPE human placenta
MIBI: PD-L1 antibody staining (cyan) of FFPE human placenta, counterstained with dsDNA (magenta)
IHC: PD-L1 antibody staining of FFPE human tonsil
MIBI: PD-L1 antibody staining (cyan) of FFPE human tonsil, counterstained with dsDNA (magenta)
Background: Programmed cell death 1 ligand 1 (PD-L1, CD274) binds to PD-1 and inhibits T cell activation.
Validation: Each lot of conjugated PD-L1antibody is quality control tested by MIBIscope™ analysis of stained tissue microarray using the appropriate positive and negative tissue field of views and are pathologist verified.
Recommended Usage: 1 uL of PD-L1 antibody per 100 uL staining volume using the MIBI™ Staining Protocol.
For optimal results,
MIBI technology: Learn more about MIBI™ Technology, a multiplex IHC technology with unmatched sensitivity and true subcellular resolution.
- Wimberly, H. et al. PD-L1 Expression
Correlateswith Tumor-Infiltrating Lymphocytes and Response to Neoadjuvant Chemotherapy in Breast Cancer. Cancer Immunol Res. 2015; 3(4): 326-332.
- Bindels, S. et al. Regulation of PD-L1 by SIP1 in human epithelial breast tumor cells. Oncogene. 2006; 25:4975–4985.
* Conjugate tested on human tissue.